1.بررسی اثرات آنتی اکسیدانی زنجبیل و دارچین: مروری جامع بر شواهد و مکانیسمهای مولکولی دخیل در سندرم تخمدان پلی کیستیک (PCOS) و سایر اختلالات مرتبط با استرس اکسیداتیو
Oxidative stress represents the pathophysiological basis for most disorders, including
reproductive issues. Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine disorder of women characterized primarily by irregular menstrual cycles, hyperandrogenism, and ovulatory dysfunction. In the last decades, PCOS was recognized as a systemic silent inflammation and an
oxidative disturbance-related disorder, exerting multifaceted symptoms, including metabolic. PCOS treatment should involve a personalized approach tailored to individual symptoms; however, the results are often unsatisfactory. Various supplementary treatments have been proposed to assist in the management and alleviation of PCOS symptoms. Cinnamon and ginger, known for millennia as
herbs used in spices or traditional medicine for the treatment of various diseases, are of interest in this study.
This study aims to evaluate and investigate the effects of cinnamon and ginger in PCOS patients. Using relevant keywords we searched through PubMed/MEDLINE, Science Direct, Google Scholar, and Web of Science to find animal studies, pre-clinical, and clinical studies which were then reviewed for usage. Out of all of the reviewed studies, a total of 65 studies were included in this review article. Cinnamon and ginger can affect hormonal status, lipid profile, obesity, and insulin resistance by mitigating oxidative stress and inflammation. Generally, based on current clinical evidence, it was revealed that supplementation with cinnamon or ginger had a useful impact in
patients with PCOS.
This review summarizes the antioxidative effects of ginger and cinnamon in
PCOS treatment, highlighting their potential benefits in other oxidative stress-related pathologies.
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#داروسازی دانش بنیان مهر و ماه
